Sistine Chapel. The Sistine Chapel is a chapel in the Apostolic Palace, the official residence of the pope, in Vatican City. Originally known as the Cappella Magna ('Great Chapel'), the chapel takes its name from Pope Sixtus IV, who restored it between 1477 and 1480. Since that time, the chapel has served as a place of both religious and functionary papal activity. Today, it is the site of the papal conclave, the process by which a new pope is selected. The fame of the Sistine Chapel lies mainly in the frescos that decorate the interior, most particularly the Sistine Chapel ceiling and The Last Judgment by Michelangelo.